Predictors of interleukin‐33 and thymic stromal lymphopoietin levels in cord blood

Predictors of interleukin-33 and thymic stromal lymphopoietin levels in cord blood

BACKGROUND The fetal immune system is a critical window of development. The epithelial cell-derived cytokines, thymic stromal lymphopoietin (TSLP), and interleukin-33 (IL-33) have received attention for their role in allergic responses but not been studied during this critical window. The objectives were to assess correlations among IL-33, TSLP, and IgE in umbilical cord blood samples and ident...

Thymic Stromal Lymphopoietin-Dependent

Thymic Stromal Lymphopoietin Interferes

Thymic stromal lymphopoietin and cancer.

Originally shown to promote the growth and activation of B cells, thymic stromal lymphopoietin (TSLP) is now known to have wide-ranging effects on both hematopoietic and nonhematopoietic cell lineages. These include dendritic cells, basophils, mast cells, B cells, epithelial cells, and CD4(+), CD8(+), and NK T cells. Although TSLP's role in the promotion of Th2 responses has been studied extens...

Thymic Stromal Lymphopoietin Amplifies